The cholesterol dibromide was then debrominated with sodium iodide13 and the cholesterol recrystallized from alcohol, m. p. 146.7-147.5°. Dihydrocholesterol.-This compound was prepared from cholesterol by the method given in "Organic Syntheses.''14 It had a melting point of 142.0-142.6°.Dioxane.-Dioxane was purified as before.1 Acknowledgment.-We are grateful to Dr. C. R. Scholz of Ciba Pharmaceutical Products Inc. for supplying nine steroids and to Professor C. R. Noller of Stanford University for the three sapogenins used in this study.
The fluorination of CCl3CCl=CCl2 to CF3CC1-=CCU is exceedingly easy because the CC13 group is made "allylic" by the double bond once removed.1 This activating effect is not restricted to just one group: in (CC13)2C=C(CC13)2, the chlorine atoms are all "allylic.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.