Table 1. Linear regression equations and ApH/min. for the normal subjects and the two groups of patients who differed significantly from the normals as well as from each other.
Ill a recqnt review (2) Furchtgott concluded that death will result from ionizing radiations before neural changes can be observed except in cases where the body is adequately shielded and the head only is radiated. Thus, no behavioral changes will be found in activities mediated directly by the nervous system, but, Furchtgott feels, decrements in learning could be found as a consequence of changes in rionassociative factors such as motivation and perception of stimuli. Blair and Arnold (1), however, found that radiating only the heads of rats with 2500 r. produced better retention of a learned maze habit during a 25-to 80-day interval after X radiation. The present study was designed to determine the effects of a high dosage (5000 r.) of restricted-area cranial X radiation, on maze acquisition.
METHOD SubjectsThe ,5' s were 67 experimentally naive, male albino rats of the Sprague-Dawley strain. They were 105 days old at the beginning of the experiment.
ApparatusThe maze was a 14-unit T maze of the Tolman-Honzik pattern. Each unit had side baffles, a nonretracing door, and a hardware-cloth top and bottom.A restricted-area exposure cylinder 3 was used to obtain brain radiation. This cylinder, made of lead sheeting, was designed in such a way that the animal's body was completely shielded during radiation except for an oval exposure area 11 mm. wide and 13 mm. long directly over the brain.X radiation was obtained through use of a Westinghouse 150-kv. industrial unit.
The use of the feedback principle in monitoring as well as in continuous control situations is proposed. A simple feedback model is discussed and the associated variables identified. These include frequency of observation and response, sensitivity, time constants in feedback and control and reversibility of control. Ten monitoring or vigilance experiments are analyzed in terms of the model.
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