The classification of Alzheimer’s disease (AD) using deep learning methods has shown promising results, but successful application in clinical settings requires a combination of high accuracy, short processing time, and generalizability to various populations. In this study, we developed a convolutional neural network (CNN)-based AD classification algorithm using magnetic resonance imaging (MRI) scans from AD patients and age/gender-matched cognitively normal controls from two populations that differ in ethnicity and education level. These populations come from the Seoul National University Bundang Hospital (SNUBH) and Alzheimer’s Disease Neuroimaging Initiative (ADNI). For each population, we trained CNNs on five subsets using coronal slices of T1-weighted images that cover the medial temporal lobe. We evaluated the models on validation subsets from both the same population (within-dataset validation) and other population (between-dataset validation). Our models achieved average areas under the curves of 0.91–0.94 for within-dataset validation and 0.88–0.89 for between-dataset validation. The mean processing time per person was 23–24 s. The within-dataset and between-dataset performances were comparable between the ADNI-derived and SNUBH-derived models. These results demonstrate the generalizability of our models to different patients with different ethnicities and education levels, as well as their potential for deployment as fast and accurate diagnostic support tools for AD.
Nowadays, there have been an increasing number of illegal use cases where people try to fabricate the working hours by using fake fingerprints. So, the fingerprint liveness detection techniques have been actively studied and widely demanded in various applications. This paper proposes a new method to detect fake fingerprints using CNN (Convolutional Neural Ntworks) based on the patches of fingerprint images. Fingerprint image is divided into small square sized patches and each patch is classified as live, fake, or background by the CNN. Finally, the fingerprint image is classified into either live or fake based on the voting result between the numbers of fake and live patches. The proposed method does not need preprocessing steps such as segmentation because it includes the background class in the patch classification. This method shows promising results of 3.06% average classification errors on LivDet2011, LivDet2013 and LivDet2015 dataset.
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