Tinospora crispa is a plant of the Menispermaceae family which is one of the endemic plants in Indonesia, commonly called as Brotowali. T. crispa is traditionally used to treat diabetes, rheumatism, sinusitis and fever. The purpose of this study was to determine the molecular structures of isolated compound of methanol fraction from T. crispa stem bark. Extraction using maceration method with n-hexane, ethyl acetate and methanol as solvents. The structures of compounds were elucidated with spectroscopic data ( 1 H, 13 C, DEPT 135º, HMBC, HMQC, 1 H-1 H COSY NMR, IR) and MS as well as compared with previously reported spectral data. The structure of isolated compound was finally identified as 24(R)methylcholesta-5-en-3β-ol (campesterol) by the compared of several physical and spectral data with the literature. In previously study, campesterol have antiangiogenic and anticholesterol activities.
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