Pathology imaging is broadly used for identifying the causes and effects of diseases or injuries. Given a pathology image, being able to answer questions about the clinical findings contained in the image is very important for medical decision making. In this paper, we aim to develop a pathological visual question answering framework to analyze pathology images and answer medical questions related to these images. To build such a framework, we create PathVQA, a pathology VQA dataset with 32,795 questions asked from 4,998 pathology images. We also propose a three-level optimization framework which performs self-supervised pretraining and VQA finetuning end-to-end to learn powerful visual and textual representations jointly and automatically identifies and excludes noisy self-supervised examples from pretraining.We perform experiments on our created PathVQA dataset and the results demonstrate the effectiveness of our proposed methods. The datasets and code are available at https://github.com/UCSD-AI4H/PathVQA

Within the development of the deep convolutional neural network, the great achievements had been made in the single-image super-resolution (SISR) task. However, the higher performance always comes with the deeper layers which also brings larger numbers of network operations and parameters that make it hard to implement in practice. In our work, a lightly super-resolution, named Mobile Share-Source Network (MSSN), is purposed to address these practical issues. In MSSN, a high-efficiency block, the mobile adaptive weighted residual unit, is designed to fulfill the need for the reduction in both parameters and the Mult-Adds while maintaining the performance with importing the deep separable convolution. Moreover, it brings into the Adaptive Weighted Share-Source Skip Connection, getting abundant information from the shallow layer which helps reconstruct better images. The experimental results show that our network has fewer numbers of parameters and operations than the state-of-the-art lightweight network while maintaining high reconstruction quality comparing with many state-of-the-art super-resolution methods in terms of both peak signal-to-noise ratio (PSNR) and structural similarity index metrics (SSIM).

We develop datasets and methods to perform visual question answering on pathology images.