The exploration of highly efficient visible-light-driven photocatalysts for dye degradation has received great concerns in wastewater treatment. Here, molybdenum disulfide (MoS2) and cadmium sulfide–manganese (CdS-Mn) were sequentially assembled onto titanium dioxide (TiO2) nanotube by a simple hydrothermal method coupled with successive ionic layer adsorption and reaction. A zinc sulfide (ZnS) layer was introduced as a potential barrier for performance improvement; the resultant material exhibits prominent visible-light-induced photocatalytic activity in degrading methyl orange (MO) and 9-anthracenecarboxylic acids, which is 3.16-fold, 2.00-fold, and 1.69-fold or 2.86-fold, 1.56-fold, and 1.47-fold of TiO2, MoS2/TiO2, and CdS-Mn/TiO2 systems, respectively. Furthermore, the synthesized ZnS/CdS-Mn/MoS2/TiO2 composite also possesses a high hydrogen production rate of 408.27 mmol/cm2/h out of water under visible light illumination, which is about 30.08 times greater than that of pure TiO2 and 5.18-fold and 2.52-fold of MoS2/TiO2 and CdS-Mn/TiO2, respectively. The enhanced photocatalyst performances are mainly attributed to the synergetic effects of CdS-Mn, MoS2, and TiO2, forming a Z-scheme system in the CdS-Mn/MoS2/TiO2 electrode, which not only accelerates the interfacial charge transfer efficiency but also preserves the strong redox ability of the photogenerated electrons and holes. In addition, the prepared photoelectrode is highly stable and completely recyclable over hydrogen evolution reaction and organic degradation.
A series of eight polymethoxychalcone Mannich base derivatives 2a-2h was synthesized via
the microwave-assisted Mannich reaction of natural product 2'-hydroxy-3,4,4',5,6'-pentamethoxychalcone
(1) with various secondary amines and formaldehyde. Compared to conventional heating method
(80°C), the microwave-assisted method (700W, 65°C) is efficient with short reaction time (0.5-1 h) and
good yields (74-88%). The antiproliferative activities of eight Mannich base derivatives were evaluated
in vitro on a panel of three human cancer cell lines (Hela, HCC1954 and SK-OV-3) by CCK-8 assay.
The results showed that all of the Mannich base derivatives exhibited potential antiproliferative activities
on tested cancer cell lines with the IC50 values of 9.13-48.51 µM. Some active compounds exhibited
more activity as compared to positive control cis-Platin. Among them, compound 2b revealed to
have the strongest antiproliferative activity against all the three cancer cell lines with IC50 values ranging
from 9.13 to 11.24 µM.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.