Objective: To develop and validate a model to predict seizure freedom in children undergoing cerebral hemispheric surgery for the treatment of drug-resistant epilepsy. Methods: We analyzed 1267 hemispheric surgeries performed in pediatric participants across 32 centers and 12 countries to identify predictors of seizure freedom at 3 months after surgery. A multivariate logistic regression model was developed based on 70% of the dataset (training set) and validated on 30% of the dataset (validation set). Missing data were handled using multiple imputation techniques. Results: Overall, 817 of 1237 (66%) hemispheric surgeries led to seizure freedom (median follow-up = 24 months), and 1050 of 1237 (85%) were seizure-free at 12 months after surgery. A simple regression model containing age at seizure onset, presence of generalized seizure semiology, presence of contralateral 18-fluoro-2-d eoxyglucose-positron emission tomography hypometabolism, etiologic substrate, and previous nonhemispheric resective surgery is predictive of seizure freedom (area under the curve = .72). A Hemispheric Surgery Outcome Prediction Scale (HOPS) score was devised that can be used to predict seizure freedom.

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Extracting farmland from high spatial resolution remote sensing images is a basic task for agricultural information management. According to Tobler’s first law of geography, closer objects have a stronger relation. Meanwhile, due to the scale effect, there are differences on both spatial and attribute scales among different kinds of objects. Thus, it is not appropriate to segment images with unique or fixed parameters for different kinds of objects. In view of this, this paper presents a stratified object-based farmland extraction method, which includes two key processes: one is image region division on a rough scale and the other is scale parameter pre-estimation within local regions. Firstly, the image in RGB color space is converted into HSV color space, and then the texture features of the hue layer are calculated using the grey level co-occurrence matrix method. Thus, the whole image can be divided into different regions based on the texture features, such as the mean and homogeneity. Secondly, within local regions, the optimal spatial scale segmentation parameter was pre-estimated by average local variance and its first-order and second-order rate of change. The optimal attribute scale segmentation parameter can be estimated based on the histogram of local variance. Through stratified regionalization and local segmentation parameters estimation, fine farmland segmentation can be achieved. GF-2 and Quickbird images were used in this paper, and mean-shift and multi-resolution segmentation algorithms were applied as examples to verify the validity of the proposed method. The experimental results have shown that the stratified processing method can release under-segmentation and over-segmentation phenomena to a certain extent, which ultimately benefits the accurate farmland information extraction.