The low utilization efficiency of pesticides exerts an
adverse
impact on the environment and human health. Polymer-related controlled-release
nanosized pesticide systems provide a promising and efficient way
to overcome the problem. In this work, a biodegradable and light-responsive
amphiphilic polymer was synthesized via 1,1,3,3-tetramethylguanidine-promoted
polyesterification under mild conditions (low temperature, no vacuum,
and no inert gas protection). We used this polymer to fabricate a
light-triggered controlled-release nanosized pesticide system. The
herbicide, 2,4-dichlorophenoxyacetic acid (2,4-D), was selected as
a model drug to show its potential as a controlled-release pesticide
system. It was found that the 2,4-D-loaded polymeric nanoparticles
were stable without the treatment of UV, while the release rate of
2,4-D from the nanoparticles gradually increased after treatment with
UV light. Pot trial showed that the 2,4-D-loaded polymer nanoparticles
showed a good herbicidal effect. Finally, toxicity studies suggested
that the polymer can reduce toxicity to nontarget organisms.
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