In this, the first published study focusing on the efficacy of u-ACP and b-ACP in total arch replacement for type A aortic dissection, the b-ACP group did not demonstrate significantly lower 30-day mortality or PND rate compared with the u-ACP group. Future large-sample studies are warranted to thoroughly examine this critical issue.
Visible Light Communications (VLC) can provide both illumination and communications and offers a means to alleviate the predicted spectrum crunch for radio-frequency wireless communications. In this paper, we report a laser diode based white-light communications link that operates over a wide area and supports high data rates. The proposed system is a four-colour multiplexed high-speed VLC system that uses a microelectromechanical system (MEMS) mirror-based beam-steering. The system operates at record data-rates of more than 35 Gb/s (Bit Error Rate(BER) < 3.8 × 10−3) with a coverage area of 39 m2 at a link distance of 4 m. To the best of our knowledge this is the fastest VLC demonstration reported thus far. The paper also addresses issues of eye-safety, showing data rates of more than 10 Gb/s are feasible.
The neointima in the vein graft was formed initially by means of migration and proliferation of the phenotypically modulated, dedifferentiated-type SMCs and continued to thicken by means of sustained ECM accumulation, including type I collagen and decorin, in association with the prolonged presence of the dedifferentiated-type SMCs. These chronologic features in cell kinetics and ECM accumulation may contribute to the frequent occurrence of graft wall thickening that occurs in the vein grafts.
Transparent nanoceramics embedded with highly dense crystalline domains are promising for applications in missile guidance, infrared night vision, and laser and nuclear radiation detection. Unfortunately, current nanoceramics are strictly constrained by the stringent construction procedures such as super‐high pressure and containerless processing. Here, a pressureless crystallization engineering strategy in glass for elaboration of transparent nanoceramics and fibers is proposed and experimentally demonstrated. By intentional creation of a sharp contrast between nucleation and growth rates, the crystal growth rate during glass crystallization can be significantly suppressed. Importantly, this unique phase‐transition habit enables the achievement of transparent nanoceramics and even smooth fibers with extremely tiny crystalline size (≈20 nm) and high crystallinity (≈97%) under atmospheric pressure. This allows the generation of an attractive nonlinear optical response such as dynamic optical filtering and luminescence in the mid‐infrared waveband of 4300–4950 nm. These findings highlight that the strategy to switch the phase‐transition habit of glass into the unconventional crystallization regime may provide new opportunities for the creation of next‐generation nanoceramics and fibers.
Functional probes are a leading contender for the recognition and manipulation of nervous behavior and are characterized by substantial scientific and technological potential. Despite the recent development of functional neural probes, a flexible biocompatible probe unit that allows for long-term simultaneous stimulation and signaling is still an important task. Here, a category of flexible tiny multimaterial fiber probes (<0.3 g) is described in which the metal electrodes are regularly embedded inside a biocompatible polymer fiber with a double-clad optical waveguide by thermal drawing. Significantly, this arrangement enables great improvement in mechanical properties, achieves high optical transmission (>90%), and effectively minimizes the impedance (by up to one order of magnitude) of the probe. This ability allows to realize long-term (at least 10 weeks) simultaneous optical stimulation and neural recording at the single-cell level in behaving mice with signal-to-noise ratio (SNR = 30 dB) that is more than 6 times that of the benchmark probe such as an all-polymer fiber.
The edible and medicinal perennial herb dandelion is known to have antitumor, antioxidant, and anticomplement properties. However, the structural characterization and biological effects of its polysaccharides are not well understood. Here, we aimed to extract and investigate a novel polysaccharide from dandelion. A water-soluble polysaccharide, PD1-1, was successfully obtained from dandelion through ultrasonic-assisted extraction and purification using diethylaminoethyl (DEAE)–Sepharose fast flow and Sephadex G-75 columns. The results showed that PD1-1 is an inulin-type polysaccharide with a molecular weight of 2.6 kDa and is composed of glucose (52.39%), and mannose (45.41%). Glycosidic linkage analysis demonstrated that PD1-1 contains terminal α-d-Man/Glcp-(1→ and →1)-β-d-Man/Glcf-(2→ glycosidic linkage conformations. A physicochemical analysis indicated that PD1-1 has a triple helix structure and exhibits important properties, including good swelling, water-holding, and oil-holding capacities. Furthermore, PD1-1 showed good antioxidant activities in DPPH and hydroxyl free radical scavenging abilities, with IC50 values of 0.23 mg/mL and 0.25 mg/mL, respectively, and good hypoglycemic activities in α-amylase and α-glucosidase inhibition, with IC50 values of 0.53 mg/mL and 0.40 mg/mL, respectively, in a concentration-dependent manner. Results suggest that PD1-1 possesses efficacious antioxidant and hypoglycemic properties and has potential applications as a functional food ingredient.
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