AIm:To understand the mechanism of the gamma knife treating the trigeminal neuralgia. mATeRIAL and meTHods: Using the MASEP-SRRS type gamma knife treatment system, 140 Chinese patients with trigeminal neuralgia (NT) were treated in our hospital from 2002 to 2010, in which the pain relief rate reached 95% and recurrence rate was 3% only. We investigated the effect of the gamma knife treatment on the trigeminal nerve root in 20 Chinese patients with primary trigeminal neuralgia by the magnetic resonance imager (MRI) observation.ResuLTs: 1) The cross-sectional area of trigeminal nerve root became smaller and MRI signals were lower in the treatment side than those in the non-treatment side after the gamma knife treatment of primary trigeminal neuralgia; 2) in the treatment side, the cross-sectional area of the trigeminal nerve root decreased significantly after the gamma knife treatment; 3) there was good correlation between the clinical improvement and the MRI findings; and 4) the straight distance between the trigeminal nerve root and the brainstem did not change after the gamma knife treatment.
CoNCLusIoN:The pain relief induced the gamma knife radiosurgery might be related with the atrophy of the trigeminal nerve root in Chinese patients with primary trigeminal neuralgia. BuLGuLAR: 1) Trigeminal sinir kökünün çapraz kesit alanı primer trigeminal nevraljinin gamma bıçağı tedavisinden sonra tedavi tarafında tedavi edilmemiş tarafa göre daha küçük ve MRG sinyalleri daha düşüktü; 2) tedavi tarafında trigeminal sinir kökünün çapraz kesit alanı gamma bıçağı tedavisinden sonra önemli ölçüde azaldı; 3) klinik iyileşme ve MRG bulguları arasında iyi korelasyon vardı; ve 4) trigeminal sinir kökü ile beyin kökü arasındaki düz mesafe gamma bıçağı tedavisi sonrasında değişmedi. soNuÇ: Gamma bıçağı radyocerrahisinin oluşturduğu ağrı giderme primer trigeminal nevraljili Çinli hastalarda trigeminal sinir kökünün atrofisiyle ilişkili olabilir.ANAHTAR sÖZCÜKLeR: Gamma bıçağı, Trigeminal sinir kökü, Primer trigeminal nevralji, MRG
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