Peritoneal macrophages (PM) perform first-line defense activity against peritonitis, the most important complication in continuous ambulatory peritoneal dialysis (CAPD) therapy. Our longitudinal study has compared the PM function in 20 uremic patients during periods free of peritonitis since they started CAPD therapy in January 1987. The results showed that at the initiation of CAPD, there was a higher bactericidal activity, phagocytosis index, H2O2 production and interleukin-1 (IL-1), Γ-interferon (IFN-Γ) and tumor necrosis factor (TNF) production ability and MHC expression. As time went on, these progressively decreased, and by 9 months after CAPD therapy had started they were significantly lower than at the beginning. During the 1.5-year follow-up period, there was a significantly increased peritonitis rate in the period 6 months after the beginning of CAPD than in the period before the 6th month (88.3 vs. 11.7% respectively; p < 0.001). These results indicate that PM of new CAPD patients have a more active function than those of established patients. The established patients had a greater risk of peritonitis. A comparison of the immunological profiles of PM from patients who had a peritonitis history shows that phagocytosis index, bactericidal activity and IL-1 and TNF production of PM were significantly decreased during the period free of peritonitis. This result suggests that these parameters may serve as an indicator in developing peritonitis.
This study mainly used the way of the magnetic abrasive finishing (MAF) to explore the cylindrical tube of stainless steel SUS304 related to the processing characteristic and the prediction system. The self-make adjustable electricity polishing mechanism was assembled on the magnetic abrasive machine. The magnetic abrasive which was consisted of the sintered iron and Aluminum Oxide powder filled in the cylindrical stainless steel tube. Magnetic abrasive in the electromagnetic field was absorbed on the cylindrical tube to become flexible magnetic brush. It could generate adjustable pressure on the work piece surface when the magnetic brush is grinding, it could make the workpiece face polished to the mirror surface degree.
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