Objective: This prospective study aimed to evaluate inter-observer agreement of the AO/OTA and Evans/Jensen classification systems with an emphasis on the effect of reviewer experience. In addition, the level of agreement in the determination of fracture stability across varying levels of experience was evaluated. Subject and Methods: A group of 12 reviewers (6 surgeons, 3 senior residents, 3 junior residents) independently assessed 56 radiographs of intertrochanteric hip fractures and classified them using the AO/OTA and Evans/Jensen systems. Reviewers further assessed the stability of the fracture patterns. Results: Overall, higher agreement was obtained for the AO/OTA classification than with the Evans/Jensen classification. However, neither classification system met acceptable thresholds for reliability. Surgeons were unable to reliability determine if fractures were stable or unstable. Increased experience improved AO/OTA classification reliability and assessment of stability but decreased agreement in the Evans/Jensen classification. Conclusion: The AO/OTA classification should be used in favor of the Evans/Jensen classification whenever possible. Our findings suggest that surgeons’ perceptions about stability vary to a significant extent thereby necessitating clear definitions of stability.
Clinically asymptomatic patients receiving hydroxychloroquine treatment can have substantial local decreases in their retinal function, as reflected by the changes in mfERG recordings, possibly indicating a preclinical stage of drug-related toxicity.
The high resolution of the MF-ERG enables detection of small areas of retinal pathology. It thus presents a clinically useful, noninvasive method in the early diagnosis and follow-up of macular disease.
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