Integrated knowledge translation approaches are one way to facilitate knowledge exchange and support the use of research in practice. This paper explores the elements of an integrated knowledge translation approach using the Systems Enhancement Evaluation Initiative (SEEI) as a case study. SEEI was a 4-year project (2005)(2006)(2007)(2008)(2009)) that explored the impacts of new funding in Ontario's community mental health system. Here, we describe the process, relationships, and challenges of this collaborative research initiative using a building analogy: getting the right people to do the work, designing the architectural blueprints, establishing the structure, and coordinating all facets of the project. We pay particular attention to the associated constraints and benefits when conducting a large-scale multisite evaluation.Over the past few decades there has been a growing culture of accountability in health care and an accompanying expectation that health research should have a practical impact on the health system (Lomas, 1997). particular attention has been directed toward how health services research can inform policy decisions,
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