A cobalt(III)-catalyzed,
redox-neutral, intermolecular carboamination
of propiolates and bicyclic alkenes was developed. This non-annulative
coupling strategy features atom economy, high regioselectivity,
good yields, and functional groups tolerance. Such a carboamination
reaction was applied to modified phenols from the corresponding phenols
under mild conditions.
A novel method for the synthesis of C2‐quaternary indole‐3‐ones via palladium‐catalyzed one‐pot transformation of 2‐alkynyl arylazides is described. The reaction produced in moderate to excellent yields under mild conditions. This novel rearrangement of 1‐H‐indole‐3‐sulfonates represents an important contribution to the application of aryl sulfonates.magnified image
An efficient method for the synthesis of 1H-indole-3-sulfonates via palladium-catalyzed tandem reactions of 2-alkynyl arylazides with sulfonic acids has been developed. The desired products were obtained in good to excellent yields under mild reaction conditions. The reactions were shown to proceed very fast, in most cases, within 10 min.
A method to prepare polyfunctional indolin-3-ones by Pd-catalyzed one-pot insertion reaction of cyclic C-acylimines into carbon-carbon s-bonds is described. The reaction was accomplished in good to excellent yields under mild reaction conditions.
An efficient palladium‐catalyzed one‐pot two‐step reaction of 2‐alkynyl arylazides and indoles has been developed. The reaction proceeded well under mild reaction conditions and provided the 2‐(1H‐indole‐3‐yl)‐2‐phenylindolin‐3‐ones in good to excellent yields.This transformation involves a rearrangement of 1H‐indole‐3‐sulfonates generated in situ and Mannich‐type addition of indoline‐3‐ones.
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