Phase I trial participation for advanced cancer patients is often a "last resort" in an attempt to control progressive disease. It is also a necessary component mandated by our investigative community and FDA to characterize safety and mechanism via dose and schedule modulation of experimental therapeutics. Participation in phase I studies is difficult without support. The purpose of this assessment is to provide proof of principle mechanisms of support locally provided in Texas and established by nurse navigation to facilitate phase I trial patient participation. Specifically, extensive financial assistance programs exist to facilitate patient participation. Management of these opportunities through a nurse navigation program in coordination with the patient optimizes patient assistance.
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