INTRODUCTION Cystic brosis (CF) is a recessive genetic disorder caused by a mutation in the epithelial chloride channel—CFTR (CFTR). Our study's primary objective was to examine the demographic prole of cystic brosis at our specialised hospital. MATERIAL AND METHODS The current research was a hospital-based observational study of individuals suspected of having cystic brosis undertaken at the G.B. Pant Children's Hospital in Srinagar between 2019 and 2022. In this research, 200 patients were chosen according to inclusion and exclusion criteria. RESULTS Out of 25, thirteen of our patients were male and twelve were female, for a ratio of 58% males to 42% females. 40% of the patients in our research were between 1 and 24 months of age. 60% were offspring of non-consanguineous marriage. Positive patients who were married consanguineously were third-degree relatives. During the course of our investigation, we discovered that the majority of patients were from Kupwara, totaling 25% of the study group. In our study, 72% of patients presented with recurrent respiratory tract infections. CONCLUSION In our study we concluded that Cystic brosis in Kashmir is more prevalent in men with non-consanguineous marriages and in the Kupwara district.
Background Mumps is one of the oldest human illnesses known to humans. Mumps is caused by a paramyxovirus, which is a single-strand RNA virus. Mumps is characterized by painful, unilateral, or bilateral swelling of the salivary glands, in particular, the parotid glands. Methods: This is a hospital-based prospective observational study. All children of age ≤18 years, both males and females with acute onset of unilateral or bilateral tender, self-limited swelling of the parotid or other salivary gland without other apparent cause. Results: Of the 150 clinically diagnosed mumps cases, 87 (58%) were male and 63 (42%) were female (male-to-female ratio of 1.4:1). There was no case below 1 year but there were 40 cases between 1 and 5 years. The 40% belonged to the lower middle class of socioeconomic status as per Kuppuswamy’s scale, followed by the upper-middle and lower-middle class. Only 15 patients (10%) were completely immunized whereas the immunization status of 8% patients was not known, and the rest of the patients were non immunized (82%). Fever was the most common presentation (150 patients;100%), followed by parotid involvement. Parotitis was present in 146 (97.3%) cases at some point during the illness, 36 patients (24%) had unilateral and 110 patients (73.3%) had bilateral involvement. 16% of patients had multiple salivary gland involvement. Mean duration of illness was 9.0±2 days. Conclusions: Mumps is a significant public health problem to warrant investment in prevention through vaccination.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.