1 Bradyzide is from a novel class of rodent-selective non-peptide B 2 bradykinin antagonists (1-(2-Nitrophenyl)thiosemicarbazides). 7 Bradyzide is orally available and blocks bradykinin-induced hypotension and plasma extravasation. 8 Bradyzide shows long-lasting oral activity in rodent models of in¯ammatory hyperalgesia, reversing Freund's complete adjuvant (FCA)-induced mechanical hyperalgesia in the rat knee joint (ED 50 , 0.84 mmol kg 71 ; duration of action 44 h). It is equipotent with morphine and diclofenac, and 1000 times more potent than paracetamol, its maximal eect exceeding that of the non-steroidal anti-in¯ammatory drugs (NSAIDs). Bradyzide does not exhibit tolerance when administered over 6 days. 9 In summary, bradyzide is a potent, orally active, antagonist of the B 2 bradykinin receptor, with selectivity for the rodent over the human receptor.

No abstract

Pseudomorphic In0.53 Ga0.47 As/AlAs/InAs resonant tunneling diodes have been grown on InP substrates by molecular beam epitaxy. Peak-to-valley current ratios as high as 30 at 300 K and 63 at 77 K are obtained on a structure with barriers of ten atomic layers AlAs, and a well consisting of three atomic layers of In0.53 Ga0.47 As, six atomic layers of InAs, and three atomic layers of In0.53 Ga0.47 As. For comparison pseudomorphic In0.53 Ga0.47 As/AlAs with In0.53 Ga0.47 As well structures have also been fabricated. For the In0.53 Ga0.47 As well structures, peak-to-valley current ratios as high as 23 have been obtained at 300 K, and, in other devices with lower current densities, two resonances are observed at room temperature.

No abstract

In this study we use the latent variable asset pricing model to examine the pricing of A and B shares in the Chinese stock markets. The hypothesis tested is whether markets for the A and the B shares of the same companies are segmented. We document only one latent variable in both A‐ and B‐share markets. However, the latent risk premiums for the A and B shares are only weakly correlated, indicating the two‐tier markets are loosely related. The weak correlation implies the two markets reflect different fundamental forces. Additional analysis demonstrates that the Shanghai market responds to the Shenzhen market rather than the other way around.