Introduction
and Importance: Coronavirus Disease 2019 (COVID-19) has become a pandemic since the beginning of 2020. COVID-19 is also spreading very rapidly in Indonesia and so far, no definitive therapy has been found.
Case presentation
We report two cases of confirmed COVID-19 with moderate pneumonia, who received 400 ml of convalescent plasma and showed improvements in clinical, laboratory and radiological examinations.
Clinical discussion
Passive immunotherapy is generally more effective when given early. Plasma transfusion is more beneficial when given before clinical conditions become severe. Some studies have shown that therapy with convalescent plasma can contribute to a longer survival and a lower length of stay.
Conclusion
Convalescent plasma can be used as an adjunctive therapy option for patients with moderate COVID-19.
Diare akut merupakan salah satu penyebab utama morbiditas dan mortalitas. Masyarakat mulai memilih obat tradisional atau obat herbal sebagai pengobatan alternatif. Obat tradisional atau obat herbal dinilai lebih aman dan tidak memberikan efek samping seperti obat kimia. Tujuan dari penelitian ini adalah untuk mengetahui efek anti diare ekstrak daun Carica pubescens terhadap bakteri Vibrio cholerae dan Shigella dysentriae. Penelitian ini dilakukan dengan menguji aktivitas bakteri Vibrio cholerae dan Shigella dysentriae terhadap ekstrak daun Carica pubescens dengan metode sumuran yang hasilnya dapat dilihat dari terbentuknya zona hambat. Data yang diperoleh diolah menggunakan statistik uji Two Way ANOVA. Hasil penelitian menunjukkan ekstrak daun Caricap pubescens konsentrasi 100% mempunyai efek terapi terbaik karena mempunyai daya hambat terbesar terhadap bakteri Vibrio cholerae maupun Shigella dysentriae.
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