The ventrolateral caudoputamen (VLCP) is well known to participate in the control of orofacial movements and forepaw usage accompanying feeding behavior. Previous studies from our laboratory have shown that insect hunting is associated with a distinct Fos up-regulation in the VLCP at intermediate rostro-caudal levels. Moreover, using the reversible blockade with lidocaine, we have previously suggested that the VLCP implements the stereotyped actions seen during prey capture and handling, and may influence the motivational drive to start attacking the roaches, as well. However, considering that (1) lidocaine suppresses action potentials not only in neurons, but also in fibers-of-passage, rendering the observed behavioral effect not specific to the ventrolateral caudoputamen; (2) the short lidocaine-induced inactivation period had left a relatively narrow window to observe the behavioral changes; and (3) that the restriction stress to inject the drug could have also disturbed hunting behavior, in the present study, we have examined the role of the VLCP in predatory hunting by placing bilateral NMDA lesions three weeks previous to the behavior testing. We were able to confirm that the VLCP serves to implement the stereotyped sequence of actions seen during prey capture and handling, but the study did not confirm its role in influencing the motivational drive to hunt. Together with other studies from our group, the present work serves as an important piece of information that helps to reveal the neural systems underlying predatory hunting.
RESUMOA faringe é um conduto musculomembranoso responsável pela condução dos alimentos, dos líquidos e do ar. Sua anatomia é bastante complexa devido a suas conexões ósseas, musculares e mucosas. Diversos fatores podem contribuir para a interrupção das vias aéreas superiores. A síndrome da apneia do sono é uma desordem respiratória que ocorre quando as paredes do espaço aéreo faríngeo entram em colapso. A diminuição do tamanho do espaço nasofaríngeo resulta em um desequilíbrio funcional com impacto no crescimento e desenvolvimento craniofacial. Para compreender a fisiologia e patogênese da obstrução das vias aéreas superiores (VAS) é essencial o conhecimento da morfologia e do funcionamento das estruturas esqueléticas e do tecido mole. Diversos métodos são utilizados no estudo da obstrução das VAS. A imagem do espaço aéreo superior mostra informações adicionais a respeito da anatomia do fluxo aéreo. Essas informações são úteis para direcionar o tipo de tratamento a ser realizado. Descritores: Faringe • Tomografia computadorizada por Raios X • Síndromes da apneia do sono • Apneia.
ABSTRACTThe pharynx is a muscled-membranous tube responsible for the conduction of food, liquids and air. Its anatomy is quite complex due to its bone, muscle and mucous connections. Several factors may contribute to a disruption of the upper airways. The syndrome of sleep apnea is a respiratory disorder that occurs when the walls of the pharyngeal airway space collapse. When there is a size reduction of the nasopharyngeal space, the result is a functional imbalance with an impact on both craniofacial growth and development. To a better understanding of the physiology and pathogenesis of upper airway obstruction, it is essential a good knowledge of both morphology and function of skeletal structures and soft tissue. Several methods are used to study the airway obstruction. The image of the upper airspace shows additional information about the airflow anatomy. This information is useful to direct the type of treatment to be performed.
Os cursos de graduação em medicina contam com diversas atividades entre as quais, as práticas laboratoriais, que apoiam as discussões realizadas em sessões tutoriais. devido à pandemia da COVID-19, as atividades educacionais presenciais passaram a ser virtuais e, nessa nova realidade, a atividade laboratorial referente à embriologia humana foi modificada e ressignificada para o novo contexto. Nesse manuscrito descrevemos como foi realizada essa atividade para um tópico específico.
RESUMO OLIVEIRA, W. F. Análise da participação da porção rostrolateral da substância cinzenta periaquedutal (PAGrl) no comportamento de busca por droga. 2015. 84 f. Tese (Doutorado em
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