Denture base poly (methyl methacrylate (PMMA) resin is one of the most frequently used materials in denture base synthesis, but due to its poor mechanical properties, PMMA can be considered a medium for the attachment and growth of a variety of pathogenic bacteria and fungi, particularly due to PMMA's pores and rough surface. The porosity percentage and surface roughness of the PMMA resin sample was lowered in this study, which resulted in a reduction in microorganisms' surface adhesion by varying the ratios of additives such as zinc oxide (ZnO) and tri-calcium phosphate (TCP) nanoparticles with (1, 2, 3, and 10% wt percent) for each additive separately, and 3% as a combination of ZnO and TCP nanoparticles in an equal ratio. Additionally, mechanical features such as surface hardness are developed, which is a critical attribute for polishing and easy finishing, as well as offering great scratch resistance during denture base cleaning. These results indicated that when compared to the other groups, PMMA (ZnO wt. 1%) and TCP-wt. 1%) reinforced composite resins demonstrated the best optimum properties. Additionally, it was discovered that adding 1% of NPs improved the mechanical qualities, which benefited the biological properties by reducing bacterial adherence to the PMMA composite resin.

The fresh and brackish groundwater resources in the State of Kuwait are restricted to two main water-bearing formations (aquifers). These are the Dammam Formation and Kuwait Group. The Kuwait Group aquifer is generally unconfined, i.e., water table condition, whereas the Dammam fractured limestone Formation is a confined-semi confined aquifer. The quality of groundwater in Kuwait varies from brackish in the southwest to brine in the northeast of Kuwait. Fresh groundwater bodies of TDS less than 1000 mg/l occur on saline groundwater of TDS 100,000 mg/l in the north and the northeast, e.g. Raudhatain and Umm Al-Aish water fields. Generally, the water table varies from zero at the Arabian Gulf Coast to about 90 m below the surface in the southwest. Significant ongoing and future groundwater projects include monitoring groundwater level and water quality, establishing hydrological, geological and hydrochemical databases, reducing groundwater levels, long-term monitoring for groundwater quality e.g. Raudhtain and Um-Al Aish freshwater reservoirs and environment treatment of groundwater reservoirs. The current study discusses the following parts: groundwater quality, groundwater geology, aquifer systems, Al-Raudhatain freshwater field, groundwater misuse and consequences (case of Wafra Agricultural Area), and Monitoring water ponds and saline soils, Al Wafra Agricultural Area (2008–2011).

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Background People are living longer, with more chronic conditions and are prescribed more medications according to disease specific guidelines. The WIDE Review is an innovative model of comprehensive medication review devised to treat the whole patient. Frail patients are twice as likely to be prescribed inappropriate medications and are more vulnerable to their harmful effects. Use of the STOPP/START criteria and the Medication Appropriateness Index (MAI) have been shown to improve patient outcomes. This study examined the impact and cost effectiveness of pharmacist led WIDE Reviews. Methods This quantitative prospective cohort study was conducted over 8 weeks in a Model 3 hospital. Inclusion criteria: inpatients age > 65 years; prescribed > 6 regular medications and screened positive for frailty (PRISMA 7 score >3). Critically ill patients were excluded. Eligible patients were randomly allocated to intervention or control group. The intervention group received a pharmacist led WIDE Review: Wholistic (establishing patients' priorities), Integrated (collaborating with primary care providers), Deprescribing Evaluation of medication harms versus benefits. Medications were screened using the STOPP/START criteria and the MAI was calculated. In conjunction with the patients and their consultants, deprescribing plans were devised and communicated to their GPs and community pharmacists Results A total of 20 intervention and 20 control group patients were enrolled. Patient characteristics (age, sex and length of stay) were similar for both groups. 65% of STOPP and 62% of START criteria were addressed in the intervention group versus 12% and 5% respectively in the control group. In the intervention group 83 medications were stopped, 23 dose reduced and the total MAI score was reduced by 64%. Cost savings to the annual drug budget alone represented a 9:1 return on investment of hospital pharmacist time. Conclusion Pharmacists performing WIDE Reviews significantly improved medication appropriateness and realised compelling cost savings. A larger scale study of this innovative approach to medication review is planned.