We report a rare case of recurrent bilateral superficial vein thrombosis (SVT) in a 45-year-old former smoking male with hereditary hemochromatosis on anticoagulation therapy with unremarkable hypercoagulable workup. This case report adds to the growing evidence that hemochromatosis is one of the rare causes of recurrent SVT, and thrombosis can still occur despite full-dose anticoagulation. Future studies assessing optimal management of the recurrent SVT in hemochromatosis patients are warranted.
We have reported a rare case of DVT in a 25-year-old patient with a known case of Protein S deficiency with INR within therapeutic index. He was seen in the ED and transferred to the Medical ward after diagnosis in the ED using doppler US. The patient was successfully treated with heparin and warfarin with a higher than usual optimal INR. This case adds to the growing evidence that PS deficiency is one of the rare causes of DVT, and also raises awareness that thrombosis can still occur in the current optimal INR for such patients. This case report necessitates the revision of what should be the optimal INR for patients with Protein S deficiency who develop thrombosis in the current optimal INR.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.