Objective: Review relationships among circadian clocks, core body temperature (CBT), and fertility in women. Methods: Scoping literature review. Results: Circadian clocks are a ubiquitous adaptation to the most predictable environmental events-the daily cycles of light and dark. Core body temperature (CBT) also follows a circadian rhythm. Additionally, CBT is tightly controlled by a combination of neuronal circuits that begin in the hypothalamus and involve many other portions of the brain as well as a wide range of peripheral mechanisms. In women with normal reproductive function, the diurnal temperature pattern for CBT is strongly influenced by the menstrual cycle of reproductive hormones, primarily estradiol and progesterone, which modulate the activity of hypothalamic neural circuits involved in body temperature control, resulting in an infradian CBT rhythm. Conclusions: Analysis of CBT via continuous recording reveals patterns in the interactions of circadian and infradian CBT rhythms capable of accurately predicting the fertility window and hormonal patterns suggesting oligo-ovulation and subfertility. New wearable technologies can facilitate employment of hormone-associated changes in CBT for pregnancy planning and offer clinical insight to infertility and menopause.
gestation and SAB were examined using Pearson/Spearman correlations, logistic regressions, and receiver-operating characteristic (ROC) curves. FHR_min, SAC_min, and CRL_min were positively correlated with each other (P,.05) and each was negatively correlated with SAB (P,.05). Regression analyses revealed that maternal age and CRL_min were not significant predictors for SAB unlike FHR_min and SAC_min. With one unit increase in FHR_min and SAC_min, the odds of SAB were reduced by 4% and 22%, respectively.CONCLUSION: FHR and SAC can be useful in predicting miscarriage after ART. There is a decrease in miscarriage rates as minimum FHR and minimum sac size increase. Further studies need to be conducted to determine which other parameters can predict a decrease risk of SAB.
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