A case of extranodal NK/T cell lymphoma (nasal type) with skin lesion as the first manifestation is reported. A 82 year old female presented with fever for 10 days, and mass with ulceration on right shoulder for 4 days. Clinically, a walnut-sized red mass with local ulceration and scab can be seen on the right shoulder. Part of the lesion had rupture scab. A circular-like infiltrated dark red plaque with a diameter of about 4cm can be seen on the right chest, with yellow and white dry secretion in the center. Multiple patches of dark red spots from coins to walnuts can be seen on the trunk and limbs. Based on skin lesions, histological, immunohistochemical staining and EBER in situ hybridization, a diagnose of primary cutaneous extranodal NK/T cell lymphoma, nasal type was made.
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