Abstract.A novel plant-induced lysosomal storage disease was observed in goats from a village in Mozambique. Affected animals were ataxic, with head tremors and nystagmus. Because of a lack of suitable feed, the animals consumed an exotic hedge plant growing in the village that was identified as Ipomoea carnea (shrubby morning glory, Convolvulaceae). The toxicosis was reproduced by feeding I. carnea plant material to goats. In acute cases, histologic changes in the brain and spinal cord comprised widespread cytoplasmic vacuolation of neurons and glial cells in association with axonal spheroid formation. Ultrastructurally, cytoplasmic storage vacuoles in neurons were membrane bound and consistent with lysosomes. Cytoplasmic vacuolation was also found in neurons in the submucosal and mesenteric plexuses in the small intestine, in renal tubular epithelial cells, and in macrophage-phagocytic cells in the spleen and lymph nodes in acute cases. Residual alterations in the brain in chronic cases revealed predominantly cerebellar lesions characterized by loss of Purkinje neurons and gliosis of the Purkinje cell layer. Analysis of I. carnea plant material by gas chromatography-mass spectrometry established the presence of the mannosidase inhibitor swainsonine and 2 glycosidase inhibitors, calystegine B 2 and calystegine C 1 , consistent with a plant-induced ␣-mannosidosis in the goats. The described storage disorder is analogous to the lysosomal storage diseases induced by ingestion of locoweeds (Astragalus and Oxytropis) and poison peas (Swainsona).Most lysosomal storage diseases are genetic disorders, 32 but a few are induced by the ingestion of toxic plants such as the locoweeds (Astragalus and Oxytropis spp.) from North America, South America, and China 36 and the poison peas (Swainsona spp.) found in Australia. 13,15,25 These plants belong to the family Fabaceae (Leguminosae) and contain the indolizidine alkaloid swainsonine, an inhibitor of lysosomal ␣-mannosidase and mannosidase II. 12,28 The action of swainsonine results in a lysosomal storage disorder that closely mimics ␣-mannosidosis, characterized by the accumulation of incompletely processed oligosaccharides rich in ␣-mannosyl and ␤-N-acetyl glucosamine moieties. 2,12 Histologically, there are cytoplasmic vacuoles in cells of the nervous system and other tissues. Neurons, as is the case in most lysosomal storage diseases, are most consistently affected because

In the genus Solanum L. (Solanaceae), subgenus Leptostemonum (Dunal) Bitter, section Acanthophora Dunal has four representatives in the Flora of southern Africa region (South Africa. Lesotho, Swaziland, Namibia. Botswana), namely  S. aculeatissimum Jacq.. S. capsicoides Allioni. S. mammosum L. (cultivated only) and S. viarum Dunal. Section  Ton a Nees has two representatives in southern Africa, namely S.  chnsotriclium Schltdl. (S.  hispidum auctt. non Pers.) and S.  ton um Sw.; both are naturalized weeds.  Solanum capsicoides, S. viarum and S.  torvum have not been listed before for southern Africa. All are introduced species native to the New World. Descriptions, discussions, illustrations and distribution maps of the naturalized species are presented, as well as keys to the species of both sections.

Alterations to the inventory of about 24 000 species and infraspecific taxa of bryophytes and vascular plants in southern Africa are reported for the year 1987. The inventory, as presently maintained in the Taxon component of the PRECIS system, contains the accepted name for each taxon, synonyms previously in use as accepted names during the past half-century, and literature references necessary to identify species in each genus and to establish the synonymy. The inventory is updated as new research affecting plant classification in southern Africa is published. During 1987 there were 678 alterations, representing about 2,8% of the total number of taxa.a

In the genus Solanum L. (Solanaceae), subgenus Leptostemonum (Dunal) Bitter, section Giganteiformia (Bitter) Child has four representatives in the Flora of southern Africa region (South Africa, Namibia. Botswana. Swaziland. Lesotho), namely S. giganteum Jacq.. S. goetzei Dammer, S. tettense Klotzsch var.  renschii (Vatke) A.E.Gonsalves and S. tettense Klotsch var.tettense. Descriptions, discussions, distribution maps and keys are presented, as well as an illustration of  S. goetzei.