The aim of the present work was to study the effect of two anticoccidial drugs namely diclazuril and semduramicin on the immune response of briolers. Birds were divided into three equal groups, each of 50 chicks. The 1 st .group received semduramicin (25 ppm). The 2 nd group received diclazuril (1ppm) and 3 rd group received only basal ration (control). All groups were vaccinated against Newcastle virus at 18 days and were challenged with a virulent strain of ND at the 21th day of age. Blood samples were collected from
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