SUMMARY In a study of the sexual contacts of patients with primary and secondary syphilis, 65 of 127 (510o) contacts at risk developed syphilis. There was no significant difference between figures for homosexuals (48/98, 49%) and for heterosexuals (17/29, 58%). Our findings are similar to those of the prepenicillin era, but the question, Why are so few contacts infected? remains unanswered.
I have found in the investigation of patients with Raynaud's phenomenon ("secondary" Raynaud's), utilizing oesophageal motility studies, that those patients with no oesophageal symptoms in whom evidence of aper.stalsis or incoordination was found invariably developed scleroderma. On the other hand, when there was a normal motility pattern scleroderma did not develop. This simple investigation greatly helps when considering the prognosis and the natural history of Raynaud's phenomenon.-I am, etc.
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