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Ni(C2H4)(C~8H~sP)2], C38H34NiP2, triclinic, PL a = 10.449 (3), b = 17.534(2), c = 10.078 (5) A, a = 102.88 (2), fl = 117.66 (3), y --90.23 (2) °, V = 1582 A 3, Z = 2, D c = 1.2832 Mg m -3. Final R = 0.044 for 6200 observed reflections. The double bond in the ~r-bonded ethylene is lengthened to 1.391 (5)A. The four protons are situated in a plane 0.17 (1) A from the C atoms.

803this is (+)-synclinal in the title compound. However, in classical 6,7-benzomorphans, conformations are restricted to the range between antiperiplanar and (-)-synclinal due to the unfavourable interactions between the C(3) and C(13) methylenes. Accordingly the C (13) methylene of the title compound occupies a volume that is normally free. It is conceivable that this volume exceeds the local boundaries of the receptor, thus leading to a global misalignment of the drug molecule. In this way, O(14) will be unable to form a hydrogen bond to the hypothetical common binding moiety in the receptor responsible for x-opioid activity. The rather promising results from a fit between the title compound and ketazocine in free space thus make little sense in the physical environment of the receptor.