Four patients with the acquired immunodeficiency syndrome and Kaposi’s sarcoma were treated with subcutaneous human recombinant γ-interferon at a dosage of 200 μg 2 × 106U twice daily for at least 28 days. While the dosage of interferon was well tolerated, progressive disease was observed in all four patients studied. These results might be due to the selection of the patients presenting advanced stages (3 out of 4) with recurrent disease after previous chemotherapy.
In postmenopausal cN0-patients axillary dissection should be replaced by axillary irradiation, since it offers the same chance for cure with much lower morbidity.
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