The aim of the study was to investigate the relationship between the presence of depressive symptoms and certain dimensions of personality in hemodialysis patients. The study included 93 subjects of both sexes, aged 24-78 years. All subjects were undergoing hemodialysis treatment for terminal stage renal insufficiency. The presence of depressive symptoms was operationally defined by the factor scores for the first principal components on the Beck Depression Inventory. Five personality dimensions were operationally defined by the factor scores for the first principal components on each of the five scales of the Big Five Inventory. The following dimensions of personality were assessed: neuroticism, extraversion, openness, agreeableness, and conscientiousness. The relationship between the five dimensions of personality and the presence of depressive symptoms was analyzed by the multiple regression analysis. The results showed that personality dimensions are significantly connected with the occurrence of depressive symptoms (R = 0.729; R2 = 0.532; F (5,87) = 19.822; p = 0.000). Two partial predictors were significantly connected with depressive symptoms. They were higher degree of neuroticism (beta = 0.082, p = 0.000) and a lower degree of openness (beta = -0.235, p = 0.016).
Istraživanje je sprovedeno u cilju ispitivanja povezanosti različitih aspekata kvaliteta života sa pojavom depresivnosti među pacijentima sa hroničnom bubrežnom insuficijencijom na hemodijaliznom tretmanu. Istraživanje je sprovedeno na uzorku od 93 ispitanika, oba pola, uzrasta od 24 do 78 godina. Svi ispitanici su usled terminalnog stadijuma bubrežne insuficijencije bili podvrgnuti hemodijaliznom tretmanu. Konstrukt kvaliteta života pacijenata na hemodijaliznom tretmanu je operacionalizovan preko 80 – ajtemske Kratke skale za ispitivanje kvaliteta života i bubrežne bolesti (KDQOL), dok je pojava depresivnosti operacionalno definisana sumacionim skorom na Bekovoj skali za ispitivanje depresivnosti. Kratka skala za ispitivanje kvaliteta života i bubrežne bolesti (KDQOL) sadrži 19 supskala koje mere različite aspekte kvaliteta života. U cilju što ilustrativnijeg prikaza povezanosti kvaliteta života i pojave depresivnosti, početni broj supskala je redukovan na tri osnovna domena kvaliteta života, pri čemu je svaki od domena predstavljen preko faktorskih skorova prve glavne komponente. Prve glavne komponente su imenovane kao Fizički aspekti kvaliteta života, Emocionalno-socijalni aspekti kvaliteta života i Lična percepcija bolesti. Višestrukom regresionom analizom ispitivana je povezanost ova tri aspekta kvaliteta života na pojavu depresivnosti. Ustanovljeno je da je sa pojavom depresivnosti povezano lošije postignuće u domenu Emocionalno-socijalni aspekti kvaliteta života i lošije postignuće u domenu Lična percepcija bolesti.
Localization of brain lesions in acute ischemic stroke has a significant effect on performance in various cognitive domains. The aim of the study was to determine whether there is association between different locations of ischemic brain lesions and different cognitive domains. The study included 40 acute ischemic stroke patients (26 male and 14 female, aged 45-78 years, with 8-16 years of education). Lesion location was visualized using brain computerized tomography, whereas performance in different cognitive domains was assessed using an extensive neuropsychological test battery. The following domains were evaluated: executive function, language, immediate recall, delayed recall, attention, divergent reasoning, and visual-constructive performance in two dimensions. A series of categorical regression analyses were applied. The results showed a significant association between the domains of executive function and language and a set of predictors related to lesion location. Global brain atrophy was found to be a significant partial predictor of performance in all cognitive domains, with higher degrees of global brain atrophy correlating with poorer performance in each of the studied domains. Combined (cortical-subcortical) lesions and unilateral lesions were both found to be significant partial predictors for language, with a higher lesion load being associated with poorer language performance. Combined lesions were also a significant partial predictor for delayed recall, with a higher lesion load correlating with poorer performance in the delayed recall domain.
Depressive symptoms and cognitive impairment frequently occur already in the acute phase of ischemic stroke. The aim of the study was to determine whether there was an association between depressive symptoms and different domains of the cognitive status in acute ischemic stroke patients and to identify cognitive domains that significantly correlated with the presence of depressive symptoms. The study comprised 40 acute ischemic stroke patients (26 men and 14 women) aged 45-78 years, with 8-16 years of education. The presence of depressive symptoms was assessed using the self-reported Beck's Depression Inventory (BDI), whereas the cognitive status was evaluated using a comprehensive neuropsychological testing battery measuring performance in different cognitive domains. The following domains were evaluated: executive function, language, immediate recall, delayed recall, attention, divergent reasoning, and visual-constructive performance in two dimensions. The multiple regression analysis was applied. The results showed a significant association between the presence of depressive symptoms and different cognitive domains. The domain of language was found to be a significant partial predictor of depression, with poorer performance in this domain correlating with a higher prevalence of depressive symptoms
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