The optimum treatment for osteoarthritis is a combination of education, medication, weight reduction, and exercise. However, the adherence to exercise decreases with treatment duration. This study aims at determining the effectiveness of a home exercise program in patients with knee osteoarthritis delivered through a brochure or videotape to improve compliance, pain and function; and also in the reduction of paracetamol intake. Type of study This is a single-blind, randomized, controlled study in a home setting. Participants One hundred and two participants with knee osteoarthritis were included in the study. Intervention: The participants were randomly assigned into video and brochure groups and instructed to perform the exercises for six months. They were evaluated for one month during the program and immediately after the end of the intervention. Outcome measures were pain using the Visual Analog Scale, modifi ed Knee Outcome Survey-Activities of Daily Living Scale, 6-minute walk test (6MWT), compliance, and paracetamol intake. Results There were signifi cant improvements in all outcome measures from baseline to one and six months in both groups. However, there was no signifi cant difference between the mean change in all the outcome measures except for the mean change in the distance walked in the 6MWT at one and six months, which was signifi cantly higher in the brochure group. Compliance to exercise and paracetamol intake decreased from one to six months in both treatment arms but was not statistically different for both groups. Conclusion The provision of a home exercise program using either video or brochure could be effective in the management of osteoarthritis.