The reactions of
cis
-[Pt(OAc)
2
(DMSO)
2
] with 2 equiv of
sym N
,
N
′,
N
″-triarylguanidines,
[ArN=C(NHAr)
2
], in toluene under reflux condition
for 8 h afforded six-membered
cycloplatinated guanidines, [Pt{κ
2
(
C
,
N
)}(OAc){κ
1
N
(ArN=C(NHAr)
2
)}] [
sym
= symmetrical; Ar = 2-MeC
6
H
4
(
1
) and 2,4-Me
2
C
6
H
3
(
2
)], in 82 and 84% yields, respectively.
The salt metathesis reaction of
1
with 1 equiv of AgTFA
in CH
2
Cl
2
at room temperature (RT) afforded
[Pt{κ
2
(
C
,
N
)}(TFA){κ
1
N
(ArN=C(NHAr)
2
)}] (
3
) in 94% yield. The reaction of
cis
-[Pt(TFA)
2
(DMSO)
2
] with 1 equiv of [ArN=C(NHAr)
2
] in toluene under reflux condition for 8 h afforded six-membered
cycloplatinated guanidines, [Pt{κ
2
(
C
,
N
)}(TFA)(DMSO)] [Ar = 2-MeC
6
H
4
(
4
), 4-MeC
6
H
4
(
5
), 2,4-Me
2
C
6
H
3
(
6
),
and 2-(MeO)C
6
H
4
(
7
)], in ≥73%
yields. The reaction of
trans
-[PtCl
2
(PhCN)
2
] with 2 equiv of [ArN=C(NHAr)
2
] in toluene
under reflux condition for 48 h afforded
trans
-[PtCl
2
{ArN=C(NHAr)
2
}
2
] [Ar = 2-MeC
6
H
4
(
8
) and 2,4-Me
2
C
6
H
3
(
9
)] in 90 and 45% yields, respectively.
Complexes
8
and
9
were separately refluxed
in MeOH for 8 h to afford six-membered cycloplatinated guanidines,
[Pt{κ
2
(
C
,
N
)}(μ-Cl)]
2
(
10
and
11
), in 93 and 96% yields,
respectively, with concomitant formation of the respective guanidinium
salts, [(ArNH)
3
...
