Background:Human immunodeficiency virus (HIV) virus, causative agent in acquired immunodeficiency syndrome, is fast becoming a major threat in the Indian subcontinent, with an estimated 3.7 million persons being infected with HIV. HIV infection is complicated by various opportunistic infections (OIs) such as tuberculosis (TB), candidiasis, herpes zoster, Pneumocystis jirvoceii, cytomegalovirus (CMV) etc., This study carried out to know the clinical profile of HIV patients with OIs.Methods:A case series study was carried out at a tertiary care hospital in Bellary, Karnataka, India. A hospital based case series study was conducted among 164 HIV patients with OIs admitted to various wards as well as attending outpatient department at Vijayanagara Institute of Medical Sciences Hospital, Bellary during Jan 2013 to Nov 2013. Both primary and secondary data was collected to gather information on clinical profile. The statistical tests used were descriptive statistics and independent t test.Results:Among 164 patients, 29.3% were females and 68.3% males. High proportions of patients were observed in 28-37 years of age group and heterosexual route was the most common mode of transmission. TB (50%) is the most frequent OI followed by candidiasis (49%), pneumocystis (16%) and others. The mean CD4 cell count in TB was 237.02/mL and in candidiasis 189.07/mL. Low values were observed in promyelocytic leukemia (18.10/mL), CMV (18.5/mL) and in toxoplasmosis (73.1/mL).Conclusions:Respiratory system was the most common system involved by OIs and most of patients with OIs had CD4 T cell count below 200/mL, whereas there were no patients in the study with counts above 500/mL.

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BACKGROUND: The human immunodeficiency virus (HIV) infection is a global pandemic.HIV continues to be a burden globally and presents serious public health problems in the developing countries, especially in India. According to the UNAIDS and World Health Organization (WHO) reports of November 2010, there are approximately 33.3 million people living with HIV/Acquired immunodeficiency syndrome (AIDS) worldwide, with a global prevalence of 0 .8%. It is now the leading cause of adult deaths in the world due to infectious diseases. HIV has become the first truly international epidemic easily crossing the oceans & borders. METHODOLOGY: A case-series study was conducted among HIV positive patients coming to the ART centre for seeking treatment at ART Centre, Vijayanagara Institute of Medical Sciences Bellary, Karnataka from March 2011 to September 2011. The sample size of the study was 500 and consecutive sampling technique is used. Permission from respective authorities and written consent from study participants was obtained. Data was collected using a pre tested semi structured questionnaire. Data was analyzed using SPSS 15.0. RESULTS: The study subjects included both males (54%) and females (46%). The educational status is less than primary schooling in 88% of study subjects and 90% are married. Hetero sexual route of transmission was most common and only 16.1% of study subjects used contraceptives. CONCLUSION: Both males and females were equally infected with HIV and productive age group is more commonly affected. Use of contraception is very low. KEY WORDS: HIV, ART, Mode of transmission INTRODUCTION: Since the recognition of AIDS pandemic, many efforts have been concentrated on the prevention of HIV transmission 1. In INDIA as stated by NACO people living with AIDS for the year 2009 estimates 23.1 lakhs which equates to a prevalence of 0.3%. Well this may seem low compared to large population of our country, but a mere 0.1% increase in HIV prevalence would increase the estimated no of people living with HIV by over half a million!!!! 2. Since India