5-Nitrosopyrimidines are important scaffolds due to their unique structural and chemical properties, notable biological activities, and utilization in the syntheses of condensed heterocycles. A series of new 4-alkylamino-6arylamino-5-nitrosopyrimidines are synthesized by intramolecular oxidation-reduction reactions of the corresponding ethyl-N-alkyl-N-(6-arylamino-5-nitropyrimidin-4-yl)glycinates. The title compounds exist as mixtures of two rotamers in CDCl3 solutions.
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