Background: Organ transplantation is one such field of modern medical sciences which has progressed over the years and has given hope for those suffering with end stage organ diseases. There are lot of advancement in technology to preserve and transplant of organs but with this technological advancement also there are still gaps in awareness regarding the subjects. To find the gaps this study was carried out in medical college students.Methods: A cross-sectional analytical study was conducted in medical college of Pune. 400 students were included in study with keeping 50% of prevalence about awareness in mind. Tool of data collection was a pre-structured questionnaire. Frequency, percentage, and chi square test Chi-square test for linear trend and was used to find associationResults: The 308 (77%) MBBS students and 92 (23%). Nursing students of all batches were included in the study. The 49.3% were aware about brain death, 68% students had fair knowledge and 10% had good knowledge about organ donation issues. The 82% students were positive, 94.5% students opined positively on policy on promotion of organ donation. The 52% students were ready to donate to anyone, while 30% students preferred to donate their organs to family members, 16% were ready to donate to their friends.Conclusions: Encouraging level of knowledge regarding organ donation, its legislative implications were present in medical and nursing students which was brought in this study.
Background: Hepatitis A virus (HAV) causes an enterically transmitted viral disease mainly affecting children and endemic in many developing countries, including India. There is an epidemiological shift with an increased incidence of symptomatic cases among children.This study was conducted to assess the seroprevalence of HAV among young children aged below 5 years and the need for universal immunization.Method: This cross-sectional study was conducted at two tertiary care hospitals in Northern India, from Apr 2014 to Jul 2015, among healthy children aged between 1 and 5 years. The sample size was calculated based on the prevalence of HAV seropositivity of 40% among children aged <10 years [16e60%] and alpha error of 5%. Analysis of serum IgG against HAV was performed by enzyme-linked immunosorbent assay method, and results were analyzed.Results: A total of 1084 children aged between 12 and 60 months were enrolled, with maleto-female ratio of 1.86:1. A total of 471 children (43.5%) were found to be positive for IgG against HAV. The seroprevalence of HAV was lower among younger children aged 12e23 months (odds ratio [OR] ¼ 0.73, 95% confidence interval [CI] ¼ 0.52e0.87, p ¼ 0.03), which was statistically significant. Seropositivity of HAV was lower among boys and families consuming safe drinking water and having improved sanitation facilities.
Conclusion:The study observed lower seropositivity against HAV among younger children, making them susceptible of contracting the disease. Possible underlying risk factors were younger age, unsafe drinking water, poor sanitation, and low education status of parents. Therefore, vaccination may be recommended as optional vaccine at one year of age, along with improved public health efforts for safe drinking water, hygiene practices, and food safety.
Background: COVID-19 pandemic is one of the greatest challenges faced worldwide and has not only posed health crisis but also had social, economic and political devastating effects. The speedy transmission risk enforced bygone practices of quarantine of healthy persons and isolation of all positive patients. The basis of all key policy making is the understanding of virus clearance from the body so that transmission can be ceased. The aim of the study was to understand the viral clearance and its’ co-relates for guiding infection control and transmission practices in COVID-19.Methods: Cross sectional study in a tertiary care hospital. A cross-sectional study of total 398 patients admitted for COVID-19 between June 2020 and November 2020 at a tertiary care centre. Statistical analysis used: frequency, percentage, and chi square test Chi square test for linear trend and was used to find association.Results: 88.19% were males and 11.81% were female patients, mean age of study participants was 34.84 years. 61.56% were symptomatic and among them 1.64% presented with severe symptoms. Mean duration to turn RT-PCR negative was 11.83 days. No significant difference in time taken to turn RT-PCR negative among asymptomatic and symptomatic cases is suggestive of no difference in viral load and its clearance in symptomatic vs asymptomatic cases.Conclusions: The disease profile of COVID-19 in our setup was alike the national disease profile and the recovery rate being 98.76%. Presence of co-morbidities affects viral clearance in COVID-19.
Background: Scrub typhus is one of the most covert diseases of present era. Diagnosis is often missed, and tools for confirming diagnosis are often not available in resource-poor setups. The aim of the study was to investigate an outbreak investigation and suggests methods of containment.
Methods: An epidemiological investigation of Scrub typhus outbreak though active and passive surveillance. Time, Place and person distribution, mean, median stand deviation were used during analysis.
Results: Cases presented with high grade fever (100%), bodyache (91%) and headache (81%). Nearly, 22% cases presented with Eschar, 16% of blood samples were positive for OX-19 antigens, 9% blood samples were sent for enzyme linked immunosorbent assay (ELISA) and were positive for IgM antibodies.
Conclusions: An outbreak of Scrub Typhus infection was successfully contained without any mortality by effectively using Chemoprophylaxis, judicial use of chemicals and personal protective measures.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.