Platelet-rich fibrin has long been used as a wound healing therapy in skin wounds and recently evidence has suggested its usage in oral cavity for different treatment procedures. This article proposes an overview of use of platelet-rich fibrin in management of complicated oral wounds. Excessive hemorrhage of the donor area, necrosis of epithelium, and morbidity associated with donor site have been described as the possible complications after harvesting subepithelial connective tissue graft, but little has been mentioned about their management. The article includes a case report of a 45-year-old male patient who showed a delayed wound healing after subepithelial connective tissue graft harvestation, which was treated with platelet-rich fibrin.
Guided bone regeneration (GBR) procedures, employing nonvital bone grafting materials and membranes, were developed to counteract the significant resorption of alveolar bone following tooth extraction. Alloplastic graft material, consisting of pure phase of -tricalcium phosphate -TCP) in the preservation of ridge volume after tooth extraction and before dental implant placement, is a well-accepted procedure. The healing potential of platelet growth factors has generated interest in using plateletrich fibrin (PRF) in ridge preservation procedures. In the present case report, -TCP bone graft was combined with PRF utilizing the principles of guided bone regeneration to build the damaged edentulous ridge to receive dental implant.
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