In this paper we investigate the stochastic modelling of a spatially structured biological population subject to social interaction. The biological motivation comes from the analysis of field experiments on a species of ants which exhibits a clear tendency to aggregate, still avoiding overcrowding. The model we propose here provides an explanation of this experimental behavior in terms of "long-ranged" aggregation and "short-ranged" repulsion mechanisms among individuals, in addition to an individual random dispersal described by a Brownian motion. Further, based on a "law of large numbers", we discuss the convergence, for large N, of a system of stochastic differential equations describing the evolution of N individuals (Lagrangian approach) to a deterministic integro-differential equation describing the evolution of the mean-field spatial density of the population (Eulerian approach).
When modeling of tumor-driven angiogenesis, a major source of analytical and computational complexity is the strong coupling between the kinetic parameters of the relevant stochastic branching-and-growth of the capillary network, and the family of interacting underlying fields. To reduce this complexity, we take advantage of the system intrinsic multiscale structure: we describe the stochastic dynamics of the cells at the vessel tip at their natural mesoscale, whereas we describe the deterministic dynamics of the underlying fields at a larger macroscale. Here, we set up a conceptual stochastic model including branching, elongation, and anastomosis of vessels and derive a mean field approximation for their densities. This leads to a deterministic integro-partial differential system that describes the formation of the stochastic vessel network. We discuss the proper capillary injecting boundary conditions and include the results of relevant numerical simulations.
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