Paraneurial adhesions have been implicated in the pathological progression of entrapment neuropathies. Surgical decompression of adhesions is often performed, with the intent of restoring nerve kinematics. The normal counterpart of adhesions, native paraneurium, is also thought to influence nerve deformation and mobility. However, influences of native or abnormal paraneurial structures on nerve kinematics have not been investigated. We measured regional strains in rat sciatic nerves before and immediately after decompression of native paraneurial tissue, and before and after decompression of abnormal paraneurial adhesions, which formed within 6 weeks of the initial decompression. Strain was significantly higher in the distal-femoral than in the mid-femoral region of the nerve before either decompression. Decompression of native and abnormal paraneurial tissue removed this regional strain difference. Paraneurial tissues appear to play a major role in distributing peripheral nerve strain. Normal nerve strain distributions may be reconstituted following decompression, even in the presence of paraneurial adhesions.
Although uncommon, traumatic diaphragmatic rupture (TDR) from blunt force injury is difficult to diagnose and can lead to serious complications if left untreated. Associated symptoms are often non-specific, which can make detection of the injury difficult. Here we present a case report of a patient who suffered a leftsided TDR after blunt trauma. Upon arrival at the emergency department, the patient denied pain but had tenderness to palpation over the epigastrium. A chest X-ray showed an elevated diaphragm on the left with mediastinal shift to the right, and a diagnosis of TDR with stomach herniation was confirmed by computed tomography (CT). The patient was admitted to surgery for reduction and repair and later discharged in good condition. This case report highlights the importance of suspecting TDR in high energy injury mechanisms presenting to the emergency department.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.