Introduction: Type 2 diabetes mellitus (DM) is a chronic metabolic condition with an increasing global prevalence. Because of this tendency, it is
rapidly becoming an epidemic in some nations, with the number of affected anticipated to quadruple in the next decade as the population ages. The
present study aimed to determine the prescribing pattern and adverse drug reaction of different groups of antidiabetic drug in type 2 Diabetes
mellitus.
Methodology: The present study was an analytical cross-sectional study conducted on total 430 type II diabetes mellitus patients attending OPD in
diabetes clinic at M.L.B Medical College, Jhansi during the study period. Various scoring system including WHO causality assessment scale,
CDSCO ADR, WHO-UMC Scale, Naranjo algorithm scale were used for assessment.
Results: Majority of patients were male [n=248(57.67%) followed by female [n=182(42.33%], respectively. Signicant patients were of middle
class [n=201(46.74%) followed by low class [n=139(32.32%] and High class [n=90(20.93%) (P<0.0001*). ADRs reported hypoglycemia was the
commonest followed by dyspepsia and epigastric pain and heart burn common. Majority of patients had HbA1c between 7.0-8.0 which is in fair
control 37.67% followed by 8.0-10.0 which is unsatisfactory 35.81% and above 10 which is in poor control 18.14% respectively. Signicant
Correlation between Medicine with ADR (p=0.0429), Total Cholesterol (p=0.0396*) and Triglycerides (p= 0.0167*).
Conclusion: According to causality assessments, majority of patients had possible causalities. Therefore, we may say that present study results
provide insight to the healthcare providers on the importance of monitoring and reporting ADR associated with the drugs.
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