Over the last several years, a worldwide trend has been observed in the use of natural products, on various infections treatment, due to their proven-by-evidence pharmacological effect. Propolis is a natural resinous substance collected by honeybees from parts of plants, buds, and exudates, mixed with bees wax and salivary enzymes. Propolis is mainly constituted by resin (50%), wax (30%), essential oils (10%), pollen (5%), and other substances (5%), such as
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