Three-component condensation of arylglyoxals, acetylacetone and urea in EtOH in the presence of small amounts of HOAc gives rise to 5-acetyl-4-aroyl-6-methyl-3,4-dihydropyrimidinones or 5-aryl-1,3-dihydro-2H-imidazol-2-ones containing an acetylacetone fragment in position 4. (1H-Pyrazol-4-yl)-1,3-dihydro-2H-imidazol-2-one derivatives were obtained via the reaction of the latter compounds with hydrazine. Doubt is cast upon an earlier report of the formation of pyrimido-pyridazines by condensation of hydrazines with 5-acetyl-4-aroyldihydropyrimidinones.
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