Dieulafoy lesions (DLs) are an uncommon nonvariceal cause of gastrointestinal bleeding. Although advanced endoscopic treatment is successful in majority, rarely radiologic intervention or surgery may be needed. Most of the reported case series described single DLs, and very limited data were available about multiple or synchronous DLs. We report a rare case of multiple DLs of the stomach refractory to repeated endoscopic interventions by hemoclips, regional diluted adrenaline injections, hemospray, and argon photocoagulation therapies and requiring total gastrectomy and roux-en-y esophagoduodenostomy surgery.
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