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The National Institutes of Health (NIH), founded in 1887, is the United States federal government's principal agency for the support of medical research both at its campus in Bethesda, Maryland, and through grants and contracts awarded to biomedical research scientists at institutions across the United States, and, to a more limited extent, in other countries. Its mission is science in pursuit of fundamental knowledge about the nature and behaviour of living systems and the application of that knowledge to extend healthy life and reduce the burdens of illness and disability.

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