Here a young patient (< 21 years of age) with a history
of infective dermatitis is described. The patient was diagnosed with myelopathy
associated with HTLV-1/tropical spastic paraparesis and treated with
interferon beta-1a. The disease was clinically established as HTLV-1-associated
myelopathy/tropical spastic paraparesis (HAM/TSP), and
laboratory tests confirmed the presence of antibodies to HTLV-1 in the
cerebrospinal fluid (CSF). Mumps, cytomegalovirus, Epstein-Barr virus,
schistosomiasis, herpes virus 1 and 2, rubella, measles, varicella-zoster
toxoplasmosis, hepatitis, HIV, and syphilis were excluded by serology. The
patient was diagnosed with neurogenic bladder and presented with nocturia,
urinary urgency, paresthesia of the lower left limb, a marked reduction of
muscle strength in the lower limbs, and a slight reduction in upper limb
strength. During the fourth week of treatment with interferon beta-1a, urinary
urgency and paresthesia disappeared and clinical motor skills improved.
Because of the clinical implications of Human Immunodeficiency Virus (HIV) status on treatment of tuberculosis (TB) and in view of the low percentage of patients in whom HIV testing is performed, we evaluated immunological features of 54 patients with newly diagnosed TB and its ability to predict HIV co-infection. All 54 patients had initially unknown HIV status and had no other Acquired Immunodeficiency Syndrome (AIDS) defining illnesses. Twenty-two patients were found to be HIV seropositive and 32 were seronegative. The median CD4 and CD8 counts were statistically different between the HIV seropositive and seronegative patients, however, there was overlap between the two groups. The median CD4:CD8 ratio was 0.17 in HIV seropositive patients and 1.95 in the seronegative patients and had minimal overlap (p < 0.0001). A CD4:CD8 ratio < or = 0.7 gave a sensitivity of 100%, specificity of 94%, positive-predictive value of 92% and a negative-predictive value of 100% in predicting HIV co-infection. In conclusion, HIV-co-infection in patients with newly diagnosed TB could be predicted on the basis of the CD4:CD8 ratio.
O lodo de esgoto ou biossólido é um subproduto resultante do tratamento biológico dos esgotos numa Estação de Tratamento de Efluente (ETE), cuja destinação é um dos principais problemas operacionais nas (ETEs), mas que após ser tratado e processado pode ser utilizado com fertilizante orgânico de forma segura. Este trabalho teve como objetivo avaliar o potencial do lodo de esgoto da ETE no acúmulo de nitrogênio na cultura de margarida (Leucanthemum maximum) cultivada em diferentes doses do lodo de esgoto da estação de tratamento de efluente. O experimento foi conduzido no laboratório de solos do IFBA, campus Vitória da Conquista, BA. O delineamento foi DIC, com quatro doses do lodo de esgoto da ETE proveniente da Estação de Tratamento de Efluentes (ETE) do município de Vitória da Conquista -BA, sendo assim: 0; 5; 10 e 15 Mg/ha, com três repetições. Foram determinados massa fresca e massa seca, posteriormente, o material vegetal foi moído para determinação de nitrogênio total através da digestão sulfúrica e destilação pelo método de Kjeldahl e posterior titulação. Os dados foram submetidos à análise de variância e teste de regressão pelo Programa estatístico SAEG. É possível observar que a maior dose do lodo de esgoto doméstico, favorece o maior número de folhas da margarida além de proporcionar uma maior área foliar e radicular da margarida, bem como o maior conteúdo de nitrogênio na folha, na raiz e total da margarida.
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