Functionalized indolizines were prepared by Lewis acid‐catalyzed cyclizations of 3‐(pyridin‐2‐yl)‐propiolates with enones. This new type of reaction provides a convenient and regioselective approach to ester‐substituted indolizine derivatives which are not readily available by other methods. Based on density function theory (DFT) calculations, a mechanism of the reaction has been suggested.
Octahydro-indeno-phenanthrenes, benzo-annulated steroids, were prepared by formal [3 þ 3] cyclocondensation reaction of 1,3-bis[(trimethylsilyl)oxy]buta-1,3-dienes with the silyl enol ether of 16formylestrone methyl ether.
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