The main approaches to the prevention of viral hepatitis A Abstract. Currently, the prevention of hepatitis A in populations with the intermediate level of endemicity is a significant issue. Vaccination associated with the importance of environmental and personal hygiene and sanitation are the most effective methods of prophylaxis in the world. Hepatitis A vaccination provides long-term protective effects, it is well tolerated and has less side effects. The possibility of hepatitis A vaccination should be considered, especially in the risk groups of populations with the intermediate level of endemicity for hepatitis A.

This article describes the main aspects of the epizootology and pathogenesis of Cahv-1 (canine herpesvirus), also, the clinical forms of manifestations of pathology in dogs of different ages and physiological status are described. Particular attention is paid to ocular pathologies developing at Cahv-1, such as herpetic conjunctivitis, blepharitis, ulcerative and stromal keratitis. The features of the diagnosis and differentiation of these pathologies are described. The systematic and local medicines used by us in the practice of treating dogs with herpetic eye, the principles and algorithms of their prescription are presented. The difficulties of diagnostics Cahv-1 are described, and the reasons for frequent false-negative results during PCR explained in the article. Besides additional laboratory verification methods for Cahv-1 as well as methods of prevention of herpetic infection of dogs are indicated.

The article summarizes the most up-to-date scientific research data, clinical experience of foreign colleagues and the author of the article regarding the indolent corneal ulcer in dogs. The modern view on the etiopathogenesis of the pathology is disclosed detailly. The clinical signs and forms of chronic corneal epithelial defects (CCED) are described. The entire list of drugs used for the therapeutic treatment of dogs with CCED is presented. Along with this, drugs are indicated the use of which is not rational for this type of corneal ulcers. The criteria for choosing a treatment approach and the principles of drawing up the therapeutic treatment regimens are described in the article. The method of surgical treatment, their advantages, and results are listed.

Vector-borne deceases (CVBDs) are registered in all Russia regions except of far northern, but the prevalence of CVBD infections in domestic dogs is low in most places. The main CVBDs, which have been expressed in dogs and observed by vets for previous decades are: babesiosis (in most regions), and dirofillariosys (in Krasnodar and Stavropol regions). But during few last years the vet clinics of Russia Black Sea Coast have reporting about frequent ehrlichiosis and anaplasmosis cases, and a few hepazoonosis and leichmaniosys cases.The Black Sea Coast region strongly differs from others regions of Russia, because CVBDs here are detected round the year but not only in specific season. The biggest domestic dog population in this region habits in Sochi area. One hundred dogs having specific clinical signs of CVBDs or having nonspecific clinical signs and tick history and had not regularly been treated against ticks and mosquitoes were studies at Vetpatrul vet clinic in Sochi. Blood samples were tested using the IDEXX SNAP® 4Dx® test, Leishmania SNAP® and was evaluated for CVBD using PCR: E.canis, An phagocytothilum, An.platys, Dirofilaria immitis, .D.repens, Hepatozoon canis, Babesia spp., Babesia gibsoni. CVBDs were revealed in 55 of 100 studied dogs: mono infections (38 dogs) of ehrlichiosis (26 dogs), anaplasmosis (5), hepazoonosis (4), dirofilariosis (2), borreliosis(1); mix infections (17) of all above mentioned infections plus babesiosis. Leishmaniosis was not revealed. Twenty five dogs of 100 have had specific clinical signs of CVBD: anemia, fever, weakness, anorexia, hemorrhage, renal failure, ophthalmology diseases (iridocyclitis, uveitis, chorioretinitis). Seven dogs of 100 died.