ResumoEmbora os avanços da medicina tenham possibilitado a descoberta de formas de tratamento mais efi cazes da doença do foro oncológico, o câncer continua a ser uma das doenças mais preocupantes para a comunidade científi ca e sociedade em geral. Desse modo, a respectiva pesquisa com base em referenciais bibliográfi cos, teve por objetivo geral investigar a utilização de estratégias de coping por pacientes oncológicos e os possíveis benefícios para seu quadro emocional. Em específi co, situações de doença como o câncer, as estratégias de coping podem ser utilizadas tanto pelo paciente, quanto pelos familiares, uma vez que o processo de adoecimento tem características estressantes para os personagens envolvidos, desde a suspeita diagnóstica da doença até as etapas da reabilitação e reajuste psíquico do paciente, de forma a requerer esforços de enfrentamento da situação, sendo a tarefa primordial reconquistar o equilíbrio psíquico apropriado, para auxílio na evolução clínica e psicossocial do portador de câncer. Palavras-chave: Oncológico; Coping; Câncer. AbstractAlthough advances in medicine have enabled the discovery of more effective forms of treatment of oncological disease, cancer remains one of the most troubling diseases to the scientifi c community and society in general. Thus, their research based on bibliographical references, had as main objective to investigate the use of coping strategies for cancer patients and the potential benefi ts to your emotional frame. In particular, disease conditions such as cancer, coping strategies can be used both by the patient and the family, since the disease process is stressful characteristics for the characters involved, from the suspected diagnosis of the disease until stages of rehabilitation and psychological adjustment of the patient, in order to apply coping efforts of the situation, with the primary task to regain proper mental balance, to aid in clinical and psychosocial development of cancer carrier.. Key-words: Oncological; Coping; Cancer. ResumenAunque los avances médicos, han permitido el descubrimiento de las formas más efi caces de tratamiento de la enfermedad oncológica , el cáncer sigue siendo una de las enfermedades que más preocupan a la comunidad científi ca la sociedad en general. Por lo tanto , su búsqueda en función de las referencias bibliográfi cas , tuvo como principal objetivo investigar el uso de estrategias para los pacientes con cáncer y sus posibles benefi cios a su marco emocional de afrontamiento. En particular, la situación de la enfermedad , como el cáncer , las estrategias de afrontamiento pueden ser utilizados tanto por el paciente y la familia , ya que el proceso de la enfermedad es de características estresantes para los personajes involucrados , desde el diagnóstico de sospecha de la enfermedad hasta etapas de rehabilitación y adaptación psicológica del paciente con el fi n de requerir los esfuerzos para hacer frente a la situación, con el cometido principal de recuperar el equilibrio mental adecuado , para ayudar en el desarr...
Background Trastuzumab is indicated for the treatment of patients overexpressing HER2 in metastatic breast cancer and HER-positive early breast cancer. Purpose This study aimed to evaluate the use of trastuzumab in an adjuvant setting, in the Hospital Garcia de Orta. Materials and methods This evaluation, carried out in September 2011, included all early-stage breast cancer patients who started trastuzumab in 2008 or 2009. Data source: medical records and patients' prescriptions from the cytostatic unit in the pharmacy department. Each patient was evaluated on six factors of poor prognosis (age < 50 years; invasion of lymph nodes; absence of oestrogen and progesterone receptors; tumour size > 2 cm; disease staging ≥ GIII and overexpression of the HER2 receptor). Results This study included 32 women with an average age of 49.5±11.4 years (33-75 years). Twenty-five women were clinically well (78.1%), 2 (6.3%) had metastases and 5 (15.6%) died. All patients had at least one factor of poor prognosis (over-expression of HER2). Only 1 patient had 1 poor prognosis factor, 6 had two factors of poor prognosis, 12 patients had 3, 9 patients presented 4 and 4 patients had 5 factors for poor prognosis. Statistically significant differences were found between the patients who were clinically well and those who developed metastatic disease or died, for the number of poor prognosis factor present at the time of trastuzumab prescription (p<0.05). Of all the poor prognosis factors, disease staging was the one that showed statistically significant differences between the 2 groups of patients (p<0.001). Conclusions The literature refers to disease staging as the most accurate estimate of prognosis in breast cancer. Based in our study, disease staging was also the factor of prognosis that best predicted the result of trastuzumab therapy.
Impacto da Visita domiciliária de Enfermagem ao recém-nascido/lactente/família: uma revisão sistemática da literatura Impacto de la visita domiciliaria de enfermería al recién nacido/lactante/familia: una revisión sistemática de la literatura Impact of the Nursing Home Visit to the newborn/ infant/family: a systematic review of the literature
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