Microwave ablation (MWA) is a minimally invasive thermal ablation technique that has the advantages of obtaining high intratumoral temperatures, less treatment time and large ablation region as compared to other thermal ablation techniques. The ablation region obtained during MWA procedure mainly depends on the design and type of the trocar being used. The trocar plays an essential role in the MWA system by governing the energy distribution during tissue ablation. In this study, a novel MWA trocar design has been considered to achieve concentrated ablation region along the tumor's spatial distribution. A dual tine trocar with each tine supplied with energy at different frequencies (2.45 GHz and 6 GHz) has been considered for tumor ablation. Commercially available Finite Element based software has been used (COMSOL-Multiphysics) to analyze the extent of ablation zone. Coupled bioheat and electromagnetic physics interfaces have been utilized. Results showed that the proposed trocar with tines operating at 6 GHz on both the tines leads to a large ablation region (3 cm in diameter) with spherical in shape. Irregularly shaped ablation region can also be achieved by this trocar with tines operating at different frequencies. The minimum time required for complete tumor ablation by the trocar operated at 6 GHz is 4 minutes, followed by 6 minutes for the trocar operated at 2.45 GHz. The proposed trocar can become a part of a better treatment planning system (TPS) based on tumor shape, nearby blood vessel presence, and the trocar's precise insertion.
The present article aims to compare the change in the temperature and ablation volume during Microwave ablation procedure. The microwave ablation process is carried out using Fourier and non-Fourier bioheat transfer models in the computational domain of breast tumor. The above models have been considered with the relaxation time known as thermal delay during ablation procedure at constant power and frequency. The above objective has been carried out on a heterogeneous three compartment Breast model using COMSOL-Multiphysics software, with inbuilt bioheat transfer and electromagnetic waves Physics interfaces. The simulation results show that the ablation volume is slightly greater while using Fourier bioheat transfer model as compared to the non-Fourier bioheat transfer model. Further, the temperature distribution also shows that there is a slight variation initially at the start of the ablation, i.e., Fourier heat transfer model shows nearly 2°C more temperature as compared to the non Fourier model and becomes equal as the time increases. The present study helps in establishing the better clinical procedure of Microwave Ablation technique.
The microwave ablation (MWA) of large hepatic gland tumour using multiple trocars operated at 2.45/6 GHz frequencies has been analysed. The ablation region (in vitro) obtained using parallel and non-parallel insertion of multiple trocars into the tissue has been analysed and compared with the numerical studies. The present study has considered a typical triangular-shaped hepatic gland model for experimental and numerical analysis. COMSOL Multiphysics software with inbuilt bioheat transfer, electromagnetic waves, heat transfer in solids and fluids and laminar flow physics has been used to obtain the numerical results. Experimental analysis has been conducted on egg white using a market-available microwave ablation device. It has been found from the present study that MWA operated at 2.45/6 GHz with the non-parallel position of multiple trocars into the tissue leads to a considerable increase in the ablation region as compared to the parallel insertion of trocars. Hence, non-parallel insertion of trocars is suitable to treat irregular-shaped large cancerous tumours (>3 cm). The non-parallel simultaneous insertion of trocars can overcome the healthy tissue ablation issue as well as the problem associated with indentation. Further, reasonable accuracy (with the difference being nearly ±0.1 cm in ablation diameter) has been achieved in comparing the ablation region and temperature variation between experimental and numerical studies. The present study may create a new path in the ablation of large size tumours (>3 cm) with multiple trocars of all shapes by sparing the healthy tissue.
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