The present study deals with the fabrication of copper oxide nanoparticles with high purity via ultrasonic
assisted chemical precipitation method. Synthesized CuO nano-mosquitocides rely on the polyvinyl
pyrrolidine (PVP) as stabilizing agent. Synthesized CuO nanoparticles were confirmed via UV-vis
spectroscopy, scanning electron microscope, X-ray diffraction, EDX, Fourier-transform infrared and
SEM mapping studies. The crystallite size from XRD studies revealed around 13.44 nm. The synthesized
CuO nanoparticle was further assessed for mosquito larvicidal activity against south-urban mosquito
larvae Aedes aegypti. The synthesized CuO nanoparticle displayed significant activity against Aedes
aegypti with the LD50 value of 43.95 μg/mL than precursor copper chloride dihydrate and control
permethrin with the LD50 value of 94.31 and 72.44 μg/mL.
The Chenopodium album extracts served as a capping agent in the present work to synthesize the Bi2O3 Nps. The synthesized nanoparticles were confirmed by various spectroscopic techniques. Nano-structured Bi2O3 was measured to have a mean size of 79.99nm. Anti-fungal activity of the synthesized Bi2O3 Nps was also evaluated. Bi2O3 Nps have been shown to have impressive antifungal efficacy against a variety of fungal species. It's a powerful anti-fungal medication that outperforms both plant extract and clotrimazole.
The process of mosquito control using synthetic substances having lot of hazardous effects to human
and the environment. So, there is an urgent need to develop plant based insecticides. The ethanolic
extract of medicinal plant Acalypha indica leaves was imperiled to preliminary phytochemical screening,
bioactive fraction isolation, larvicidal activity and molecular docking studies. Preliminary phytochemical
screening displayed the existence of steroids, flavonoids, alkaloids, sugars and saponins in ethanolic
extract of Acalypha indica L. The isolated bioactive compound was confirmed by using spectroscopic
methods such as GC-MS, FT-IR, NMR (1H & 13C) and elemental analyses. The spectroscopic data
confirmed the isolated compound was bis(2-ethylhexyl)phthalate (1). Compound 1 exerted more
larvicidal activity than plant powder and its ethanolic extract with an LD50 value of 38.23 μg/mL,
which was better than that of control permethrin with an LD50 value of 54.05 μg/mL. Plant powder
and ethanolic extract were moderate larvicidal effect towards C. quinquefasciatus with LD50 values of
>100 and 75.13 μg/mL, respectively. The molecular docking studies shows significant supporting
evidence for larvicidal activity.
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