Neonatal septicemia is the most important cause of neonatal mortality. A wide variety of bacteria both aerobic and anaerobic can cause neonatal sepsis. Genus Pantoea is a member of Enterobacteriaceae family that inhabits plants, soil and water and rarely causes human infections, however, Pantoea dispersa has not been reported as a causative organism for neonatal sepsis. We hereby report two neonates with early onset sepsis caused by Pantoea dispersa. Early detection and appropriate antibiotic therapy can improve overall outcome of this rare infection in neonates.
Meningitis due to Multi Drug Resistant Acinetobacter baumannii (MRAB) is a serious emerging problem in pediatric intensive care. Treatment of these patients is challenging and polypeptide antibiotic is an important option but have poor cerebrospinal fluid (CSF) penetration. We describe our experience of a successfully treated neonatal ventriculitis and meningitis due to MRAB with intraventricular polymyxin B.
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