Numerous treatment regimens for the periodontal disease seen in PLS can be found in the literature. We demonstrate successful treatment of the periodontal disease seen in this condition using mechanical therapy, systemic antibiotics, and surgical modalities; over a period of 1 year, we were able to achieve significant reductions in gingival inflammation and erythema.
The gingival enlargement was histologically consistent with the characteristic angiofibromas of tuberous sclerosis. The gingival enlargement responded very well to gingivectomy and periodontal maintenance.
A radiochemical technique for the rapid and precise measurement of glucose utilization of fresh samples of dental plaque is described. The method appears to be a sensitive indicator of the actual glycolytic ability of an organized microbial plaque including activity in the Embden‐Meyerhof pathway as well as heterolactic fermentation and the Entner‐Doudoroff pathway.
It was found that the glycolytic rate of plaque associated with periodontal pockets was significantly higher than that for plaque not so associated.
Mesenchymal Stem Cells (MSCs) have been isolated from a variety of fetal and adult tissues and are considered an ideal source for cell-based therapy due to their unique properties such as multipotency and immunomodulatory functions. The aim of this work is to observe, analyze and investigate the morphology and proliferation of human dental pulp stem cells cultured in two different culture media: Fetal Bovine Serum (FBS) or platelet lysate. These cells would be cultured for a minimum period of 14 days to 3 months. The desired outcome is a pure culture of mesenchymal stem cells. With this present study we will determine which culture mediumpromotesthe most rapid formation of a pure culture of mesenchymal stem cells derived from Dental Pulp Stem Cells (DPSC).
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